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Preparation, Characterization, Biological Evaluation and Assess Laser Efficacy for New Derivatives of Imidazolidin-4-one

Adil Hussein Dalaf
Department of Chemistry, College of Science, Tikrit University, Tikrit-Iraq.
Fawzi Hameed Jumaa
Department of Chemistry, College of Education for Women, Tikrit University, Tikrit-Iraq.
Hanaa Kaain Salih
Department of Chemistry, College of Science, Tikrit University, Tikrit-Iraq.

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Abstract

In this study, new Imidazolidin-4-one [A1-A5] compounds were prepared by the reaction of schiff base compounds with alanine in ethanol. The prepared compounds were characterized by physical properties, UV-Vis, FT-IR and 1H-NMR spectral and C.H.N analysis. TLC checked the purity for these compounds. All compounds [A1-A5] were prepared by the traditional method (reflux) and microwave technology. It was found that using the microwave method gives better results in terms of less time and, higher yield. Antibacterial behaviors were investigated against a variety of bacteria, including Escherichia coli and Klebsiella pneumonia Gram (-) ve, Staphylococcus aureus, and Staphylococcus epidermidis Gram (+) ve. The laser efficacy of the compounds [A1-A5] was evaluated after they were radiated by laser for (10, 20, 30) seconds. As the melting point and color of the substances were determined, it was discovered that they were unaffected and did not disintegrate or polymerize. Using the Chem Draw Specialist 19.0 program, the stereoisomers of the prepared compounds [A1-A5] were examined at the lowest layer stage. Using the Chem3D 19.0 program, the heat of the formulation of the compounds [A1-A5] was also investigated.

Keywords

  • Imidazolidin-4-one,
  • Biological Activity,
  • Laser Effectiveness

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Article Details

Volume 3, Issue 4, Year 2021

Published 2021-06-27

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How to Cite

Dalaf, A. H., Jumaa, F. H., & Salih, H. K. (2021). Preparation, Characterization, Biological Evaluation and Assess Laser Efficacy for New Derivatives of Imidazolidin-4-one. International Research Journal of Multidisciplinary Technovation, 3(4), 41–51. https://doi.org/10.34256/irjmt2145

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