Bulletin of Scientific Research

Extraction, Spectral Investigation and Biological Activities of Peltophorum pterocarpum (DC.) K.Heyne flower

Mohanraj V — 2025-05-16

Peltophurm petrocarpum possesses amazing pharmacological physiological actions and other uses, according to a comprehensive literature review. Peltophurm petrocarpum also has a variety of physiological benefits. This made us want to extract a novel component from its solvent using the peltophurm petrocarpum flower. An effective technique for isolating chemicals from peltophurm petrocarpum flowers is being developed. Our plan is to use a Soxhlet device at boiling temperature to separate the material by treating it with pure chloroform. Studies using gas chromatography, mass spectrometry and antibiotic activators helped to better identify the chemical. Glass plates coated with silica gel 60 (E.Merck, India Ltd.) were used for Thin Layer Chromatography (TLC). GC-MS (Hewlett-Packerd 6890/5973, equipped with an HP-5, operating at 1000 eV ionization energy) was used to examine the active extract. Standard medications were used to test the isolated compound's antibacterial and antifungal properties against a variety of species.

Effects of the Captopril- Calcium Combination in the Management of Dexamethasone-Induced Hypertension in Adult Male Wistar Rats; Its Effect on the Kidney Function and Thyroid Gland

Boluwatife C Bello — 2025-03-24

Background: Hypertension is a major cause of clinical and preclinical damage to the kidneys, heart, and other body organs. Damage to these organs manifests as cardiovascular diseases, impaired renal disease, heart failure, stroke, etc. Cardiovascular diseases are the primary cause of death in the world. Objective: This study evaluated the antihypertensive effect of the co-administration of calcium and captopril on dexamethasone-induced hypertension in adult male Wistar rats on Systolic blood pressure, Histology of the kidney, Oxidative stress level in the kidney; Catalase (CAT), Glutathione (GSH) and Superoxide dismutase (SOD), Lipid peroxidation level in the kidney (malondialdehyde (MDA), Thyroid gland histology and Renal function: urea and creatinine. Methods: Twenty-five male Wistar rats weighing 160g-200g were randomly grouped into 5 groups of 5 rats each; control group A(distilled water only), test group B (0.5 mg/kg dexamethasone injection), test group C (0.5 mg/kg dexamethasone injection and 150mg/kg calcium), test group D (0.5 mg/kg dexamethasone injection and 40mg/kg captopril tablet), test group E (0.5 mg/kg dexamethasone injection, 40mg/kg captopril tablet and 150 mg/kg of calcium after thirty minutes). Results: The combination of calcium and captopril resulted in the restoration of the kidney function loss as seen in the histology of the kidney and thyroid gland. While the administration of captopril only showed more effectiveness in the treatment of systolic blood pressure. Conclusion: These results showed that the combination of Calcium and Captopril may be used in the treatment of organ damaged by hypertension while Captopril is a potent antihypertensive.

Ethnomedicinal and Conservation Perspective Study on Sacred Trees in Hindu Temples of Chennai District

Aravindhan Veerasamy — 2025-04-28

Sacred plants are considered as the ecological and medicinal resources since they are vital part of Hindu religion, traditional therapy and cultural heritage. This ethnomedicinal and conservation study explore sacred plants that are present in 29 temples in Chennai District, Tamil Nadu. Field surveys and structured interviews were conducted by conversing with temple authorities, residents, priests, and traditional medical practitioners. 14 individual species which belong to 10 botanical families were documented. Aegle marmelos, Mimusops elengi, and Prosopis cineraria with their dual religious and therapeutic values were some of the dominant species. Ethnobotanical information has confirmed that these trees used in traditional medicine due to their medicinal properties such as anti-inflammatory, and antimicrobial actions. In addition, they are symbolically significant and highly revered by people. Conservation measures such as protective fencing and botanical information swere also documented. Temples remain custodians of sacred biodiversity in Tamil Nadu, thus highlighting the need for temple-integrated conservation that coexist spiritually and ecologically.

Integrating Functional Connectivity and Domain Adaptation for Generalizable EEG Emotion Recognition

Kishore Kanna R — 2025-05-03

Recognizing emotions using EEG signals is difficult because EEG data is not stationary, has a low signal-to-noise ratio, and varies a lot between subjects. We present a new hybrid framework called CDA-GAF (Cross-Domain Adaptive Graph Attention Fusion) in this work. It combines the strengths of Graph Attention Networks (GATs), Temporal Transformers, and Domain Adaptation to make emotion classification models more robust and generalizable. To make brain connectivity graphs for each frequency band, our method first gets functional connectivity features from EEG channels. A GAT module processes these to find spatial dependencies in EEG activity. Then, a Temporal Transformer module is used to model long-range dependencies between EEG sequences. To address cross-subject variations, we implement a domain adaptation layer utilizing CORAL loss or Domain-Adversarial Training (DANN), which aligns feature distributions between source and target subjects. We also use extra emotion supervision signals, like HRV or micro-expressions, to improve the quality of the labels by anchoring the emotional state in multiple ways. We test our model on standard datasets like DEAP, SEED, and WESAD. It does much better than baseline models at recognizing emotions in both within-subject and cross-subject settings. Our findings underscore the efficacy of integrating graph-based spatial encoding, temporal attention mechanisms, and domain adaptation for emotion recognition from EEG data.

Cost-Effective Smart Gloves for the Paralyzed Hand Rehabilitation

Priyadarshan K — 2025-05-07

Stroke is a severe, frequent, and certain as an international health problem worldwide. Stroke is among most frequent cause of mortality and one of the leading causes of disability in adults. Even with all of the amazing progress made in stroke care, the majority of stroke patients will still require PT intervention if proper care is not provided. This study aims to describe a new, improved gadget that helps stroke patients who are unable to move their hands. The proposed prototype is an accessible smart glove designed to help stroke survivors recover by continuously contracting and relaxing their muscles without the need for physiotherapy. In this project Temperature and Heartbeat sensors are interfaced to microcontroller. Vibration motor will be turned ON to activate hand movement for long time when MEMS sensor remains constant.