Abstract

India has a significant opportunity to contribute to the growing global demand for medicinal and aromatic plant products. Plants have been used for long as medicine by humans, seeing back to prehistoric eras. Among the ancient civilization’s, India have been known to be rich renowned as a rich source of medicinal herbs. Ayurveda, Siddha, Unani and Folk lore (tribal) medicines are the major systems of indigenous medicines. Among these systems, Ayurveda is most developed and widely practiced in world wide. Green plants have been synthesized and preserved a variety of secondary metabolites and phytochemical products. The medicinal plant Hygrophila auriculata belonging to Acanthaceae family and generally presents in aquatic area. It is a rare and endemic species all over the countries; the plant has been used to treat various diseases and disorders. Extracts and bioactive compounds from the plant have been found to possess antimicrobial, anthelmintic, antitermite, nephroprotective, hepatoprotective, central nervous system protective, antitumour, antidiabetic, anticataract, antioxidant, haematopoietic, diuretic, antinociceptive, anti-inflammatory, antipyretic, antimotility, aphrodisiac, neuroprotection, anti-endotoxin and anti-urolithiatic activities. In this study focused the preliminary tests are antibacterial activity for MIC, antioxidant scavenging activity using DPPH, FRAP, ABTS and Hydrogen peroxide activities, and qualitative and quantitative analysis phytochemicals and physical parameter evaluation for study plant.

Keywords

Aromatic plant, Hygrophila auriculata, Acanthaceae, Phytochemicals, Antioxidant, Diseases and Disorders,

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References

  1. A.D. Kshirsagar, K.G. Ingale, N.S. Vyawahare, & V.S. Thorve, Hygrophila spinosa: A comprehensive review. Pharmacognosy Reviews, 4(8) (2010) 167.
  2. M.S. Hussain, S. Fareed, & M. Ali, Hygrophila auriculata (K. Schum) Heine: Ethnobotany, phytochemistry and pharmacology. Asian Journal of Traditional Medicines, 5(4) (2010) 121-131.
  3. I. Liguori, G. Russo, F. Curcio, G. Bulli, L. Aran, D. Della-Morte, G. Gargiulo, G. Testa, F. Cacciatore, D. Bonaduce, P. Abete, Oxidative stress, aging, and diseases. Clinical Interventions in Aging. 13 (2018) 757–772.
  4. B. Frei, Molecular and biological mechanism of antioxidant action. The FASEB Journal. 13 (1999) 963–964.
  5. S. Md Hussain, K.F.H. Nazeer Ahmed and Md Zaheen Hasan Ansari, Preliminary Studies on Diuretic Effect of Hygrophila auriculata (Schum) Heine in Rats, International Journal of Health Research, 2(1) (2009) 59-64.
  6. A.D. Sarvananda, Premarathna, Ethnopharmacolological potential and medicinal uses of Hygrophila auriculata L. Journal of Ayurvedic and Herbal Medicine. 4(4) (2018) 185-188.
  7. A.K. Nadkarni, Indian Material Medica Popular. Prakashan Private Ltd, Bombay, India, (1978) 667- 669.
  8. M.R. Fernando, S.M.D.N. Wickramasinghe, M.I. Thabrew, E.H. Karunanayaka, A preliminary investigation of the possible hypoglycemic activity of Asteracanthus longifolia. Journal of Ethnopharmacology. 27 (1989) 7–14.
  9. A. Singh, S.S. Handa, Hepatoprotective activity of graveolens and Hygrophila auriculata against paracetamol and thioacetamide intoxication in rats. Journal of Ethnopharmacology. 49 (1999) 119–126.
  10. S. Shailajan, N. Chandra, R.T. Sane, S. Menon, Effect of Asteracantha longifolia Nees. against CCl4 induced liver dysfunction in rat, Indian Journal of Experimental Biology, 43 (2005) 68–75.
  11. U.K. Mazmudar, M. Gupta, S. Maiti, B. Mukherji, Antitumor activity of Hygrophila spinosa on Ehrlich ascites carcinoma and sarcoma 180 induced in mice, Indian Journal of Experimental Biology, 35 (1997) 473–477.
  12. P.G. Jayatilak, D.S. Pardanani, B.D. Murty, A.R. Seth, Effect of an indigenous drug (speman) on accessory reproductive fucntions of mice, Indian Journal of Experimental Biology. 14 (1976)170–173.
  13. P. Shanmugasundaram, and S. Venkataraman, Hepatoprotective and antioxidant effectsof Hygrophila auriculata (K. Schum) Heine Acanthaceae root extract. Journal of Ethnopharmacology, 8;104(1-2) (2006) 124-128.
  14. W.C. Evans, In: Bailiere Tindall WB, editor. Trease and Evans Pharmacognosy. 14th ed. London: Sauders company ltd; (1996) 191–57.
  15. O.P. Sharma, and T.K. Bhat, DPPH antioxidant assay revisited. Food Chemistry, 113(4) (2009) 1202–1205.
  16. I.F. Benzie, and J.J. Strain, The ferric reducing ability of plasma (FRAP) as a measure of ‘‘antioxidant power”: the FRAP assay. Analytical Biochemistry, 239 (1996) 70–76.
  17. R.J. Ruch, S.J. Cheng, and J.E. Klaunig, Prevention of cytotoxicity and inhibition of intracellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis, 10 (1989) 1003.
  18. H.X. Xu, and S. Lee, Activity of plant flavonoids against antibiotics resistant bacteria. Phytotherapy Research, 15 (2001) 39-43.
  19. Mahasneh, A.M. 2002. Screening of some indigenous Qatari medicinal plants for antimicrobial activity. Phytotherapy Research, 16(8): 751-753.
  20. E.J. Hong, K.J. Na, I.G. Choi, K.C. Choi, and E.B. Jeung, Antibacterial and antifungal effects of essential oils from coniferous trees. Biological and Pharmaceutical Bulletin, 27 (2004) 863–866.
  21. A. Brantner, and E. Grein, Antibacterial activity of plant extracts used externally in traditional medicine. Journal of Ethnopharmacology, 44 (1994) 35-40.
  22. B.Y. Aju, R. Rajalakshmi and S. Mini, Pharmacognostical evaluation of curry leaf (Murraya koeingii). Journal of Pharmacognosy and Phytochemistry. 7(6 (2018) 779-784.
  23. Rajakannu Pandiyan and Kaliappan Ilango, Pharmacognostical, physicochemical and phytochemical evaluation of Huberantha senjiana (Annonaceae) leaf: An endemic tree of Gingee Hills Tamil Nadu India. Journal of Pharmacy & Pharmacognosy Research. 10 (1) (2022) 158-172.
  24. G. Divya, D. Jyotirmay, and K. Mukesh, Phytochemical analysis and antimicrobial activity of some medicinal plants against selected common human pathogenic microorganisms. Asian Pacific Journal of Tropical Disease. 6(1) (2016)15–20.
  25. Bonjar, G.H.S., Nik, A.K. and Aghighi, S. 2004. Antibacterial and antifungal survey in plants used in indigenous herbal-medicine of south east regions of Iran. Journal of Biological Sciences, 4: 405-412.
  26. B. Sandeep, K Rajdeep, and S. Manisha, phytochemical analysis of medicinal plants and their antimicrobial activity, Agricultural Research Journal, 57 (3) (2020) 444-448.
  27. A.V. Rao, and M.K. Sung, Saponins as anticarcinogens. Journal of Nutrition. (1995) 717S–724S.
  28. K.T. Chung, T.Y. Wong, C.L. Wei, Y.W Huang, and Y. Lin, Tannins and human health: a review. Critical Reviews in Food Science and Nutrition, (1998) 421-64.
  29. R. Ashokkumar, and M. Ramaswamy, Phytochemical screening by FTIR spectroscopic analysis of leaf extracts of selected Indian Medicinal plants. International Journal of Current Microbiology and Applied Sciences, (2014) 395-406.
  30. M. Marimuthu, and P. Gurumurthi, Phytochemical screening and FTIR studies on wild and common south Indian legumens, Asian Journal of Pharmaceutical and Clinical Research 6(2) (2013).
  31. M. Pakkirisamy, S.K. Kalakandan, and K. Ravichandran, Phytochemical Screening, GC-MS, FT-IR Analysis of Methanolic Extract of Curcuma caesia Roxb (Black Turmeric), Pharmacognosy Journal, 9(6) (2017) 952-6.
  32. P. Margarita, and R. Quinteiro, Fourier Transform Infrared (FT-IR)Technology for the Identification of Organisms, Clinical Microbiology Newsletter. 8(22) (2000).
  33. N.S. Ncube, A.J. Afolayan, and A.I. Okoh, Assessment techniques of antimicrobial properties of natural compounds of plant origin. Current methods and future trends. African Journal of Biotechnology.7 (2008) 1797-1806.
  34. E.A. Baker, Chemistry and morphology of plant epicuticular waxes. In: Cutler DF, Alvin KL, Price CE. eds. The Plant Cuticle, London: Academic Press. (1982) 139‐165.
  35. N. Janakiraman, S.S. Sathish, and M. Johnson, UV VIS and FTIR Spectroscopic studies on Peristrophe bicalyculata (Retz.) Nees, Asian Journal of Pharmaceutical and Clinical Research. 4(4) (2011) 125-129.
  36. S. Kumar and A.K. Pandey, Chemistry and Biological Activities of Flavonoids: An Overview. The Scientific World Journal. (2013) 1-16.
  37. P.J. Dyson, and J.S. McIndoe. (2000) Transition Metal Carbonyl Cluster Chemistry, 2000 by CRC Press, Textbook - 180.
  38. F. Zeena, S.K. Prasanna, M.P. Gururaj, and K.S. Rajesh GC-MS analysis of the phytocomponents in the extract of Persea Americana. Plant Archives. 20(2) (2020) 8195-8200.
  39. P. Arulmanickam, and T. Chitra, Preliminary and Secondary Phytochemistry of the Suicidal Plant Cleistanthus collinus (Roxb.), Asian Journal of Multidisiciplinary studies, 8(2) (2020) 25-30.
  40. A. Ponmathi Sujatha, R. Michael Evanjaline, S. Muthukumarasamy, and M. Mohan, Determination of Bioactive Components of Barleria Courtallica Nees (Acanthaceae) By Gas Chromatography-Mass Spectrometry Analysis, Asian Journal of Pharmaceutical and Clinical Research. 10(6) (2017) 273-283.
  41. M.M. Amin, S.S. Sawhney, and S.J. Manmohan, Qualitative and quantitative analysis of phytochemicals of Taraxacum officinale Wudpecker, Journal of Pharmacy and Pharmocology, 2(1) (2013) 001 – 005.
  42. A.W. Bauer, W.M.M. Kirby, J.C. Sherris, and M. Turck, Antibiotic susceptibility testing by a standardized single disk method, American Journal of Clinical Pathology. 45 (1966) 493-496.
  43. A. Doss, Antimicrobial activity of Hygrophila auriculata (Schumach.) Heine and Pergularia daemia Linn. African Journal of Plant Science. 7(4) (2013) 137-142.